CRISPR-mediated
viral immunity

Designed by Nature, harnessed by Ancilia

Harnessing the natural power of CRISPR and our CoVE™ platform to tackle the virome

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About

Beneficial bacteria have
broad potential to transform the treatment of a number of diseases

Some of the bacteria that comprise the microbiome play a critical role in maintaining health

Some of the bacteria that comprise the microbiome play a critical role in maintaining health

These microbes can serve as live biotherapeutics — they have the potential to be harnessed as novel therapies for a wide range of indications

These microbes can serve as live biotherapeutics — they have the potential to be harnessed as novel therapies for a wide range of indications

However, although most focus to date has been on the bacterial components of the microbiome, at least half of the microbiome is made up of viruses

However, although most focus to date has been on the bacterial components of the microbiome, at least half of the microbiome is made up of viruses

Viruses that infect and kill bacteria are the most abundant types of viruses on the planet

Viruses that infect 
and kill bacteria are the most abundant types of viruses on the planet

Plants
Fungi
Archaea
viruses

are the most abundant 
biological entity on the planet

Bacteria
Protists
Animals
Plants
Animals
Fungi
Protists
Archaea
Bacteria
Viruses

are the most abundant 
biological entity on the planet

About

Beneficial bacteria have
broad potential to transform 
the treatment of a number 
of diseases

Some of the bacteria that comprise the microbiome play a critical role in maintaining health

These microbes can serve as live biotherapeutics — they have the potential to be harnessed as novel therapies for a wide range of indications

However, although most focus to date has been on the bacterial components of the microbiome, at least half of the microbiome is made up of viruses

Viruses that infect 
and kill bacteria are the most abundant types of viruses on the planet

Swipe left to learn more

Plants
Fungi
Archaea
viruses

are the most abundant 
biological entity on the planet

Bacteria
Protists
Animals
Plants
Animals
Fungi
Protists
Archaea
Bacteria
Viruses

are the most abundant 
biological entity on the planet

The Hidden Virome

Why viruses matter?

Viruses — tiny infectious agents that replicate solely inside the living cells of organisms are omnipresent

These viruses can limit the utility of beneficial bacteria

But bacteria are not defenseless against viruses. CRISPR-Cas, which represents nature’s first immune system, evolved in bacteria specifically to combat viruses.

Vaccines against viruses have been transformative for human health.

Leveraging CRISPR’s natural function to ‘vaccinate’ bacteria against predatory viruses will enable us to realize the full potential of beneficial bacteria as therapies and products.

But bacteria are not defenseless against viruses. CRISPR-Cas, which represents nature’s first immune system, evolved in bacteria specifically to combat viruses.

Vaccines against viruses have been transformative for human health.

Leveraging CRISPR’s natural function to ‘vaccinate’ bacteria against predatory viruses will enable us to realize the full potential of beneficial bacteria as therapies products.

But bacteria are not defenseless against viruses. CRISPR-Cas, which represents nature’s first immune system, evolved in bacteria specifically to combat viruses.

Vaccines against viruses have been transformative for human health.

Leveraging CRISPR’s natural function to ‘vaccinate’ bacteria against predatory viruses will enable us to realize the full potential of beneficial bacteria as therapies products.

Swipe left to learn more

Mission

Ancilia is harnessing the natural power of CRISPR 
to create beneficial bacterial products with immunity against destructive viruses

Mission

Ancilia is harnessing the natural power of CRISPR 
to create beneficial bacterial products with immunity against destructive viruses

Technology

At Ancilia, we are leveraging new technologies to tackle the virome

The Problem

Virome Identification 
and Targeting are Challenging

Viruses are
 exceedingly diverse

There is no universal marker sequence for viruses

Viruses are difficult to grow & culture in the lab

Technology

At Ancilia, we are leveraging new technologies to tackle the virome

The Problem

Virome Identification 
and Targeting are Challenging

Viruses are
 exceedingly diverse

There is no universal marker sequence for viruses

Viruses are difficult to grow & culture in the lab

Platform

CoVE™
Computational Virome Engine

Our CoVE™ platform tackles the uncharted territory of the virome by addressing the challenges of virome identification and characterization

The CoVE™ platform has the dual ability to computationally identify and characterize the virome and also design solutions to counter the destructive properties of specific viruses

Going forward, our CoVE™ platform will enable us to leverage our deep understanding of the virome to tackle a broad range of other virome-associated applications

Platform

CoVE™
Computational Virome Engine

Our CoVE™ platform tackles the uncharted territory of the virome by addressing the challenges of virome identification and characterization

The CoVE™ platform has the dual ability to computationally identify and characterize the virome and also design solutions to counter the destructive properties of specific viruses

Going forward, our CoVE™ platform and CRISPR tools and technologies will enable us to leverage our deep understanding of the virome to tackle a broad range of other virome-associated applications

Ancilia Bio

Harnessing the natural power of CRISPR and our CoVE™ platform to tackle the virome

Our proprietary CRISPR tools and technologies enable us to implement these solutions to develop new classes of live biotherapeutics and other bacterial products for a range of applications.

Therapeutics
Agriculture
Industrial Biotechnology